Rituximab – could it be a treatment for MECFS?

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We have updated our 2012 leaflet about rituximab.

In 2012, Dr Charles Shepherd weighed up for the evidence for using this anti-lymphoma drug as a treatment for ME/CFS. This followed the publication of encouraging results from a small clinical trial in Bergen, Norway, that assessed the use of rituximab in treating a small group of people with ME/CFS.

The trial looked promising – certainly in a group of people who had a form of immune dysfunction as part of their illness.

Then, in November 2017, unofficial word come through from Norway that negative results had been drawn from the study. The results now need to be published in a peer-reviewed journal before any firm conclusions can be drawn.

This Management File looks at the drug in detail, discusses the results of the clinical trial and outlines the MEA’s current position on future research by the Norwegian group.

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